Search on: FC FRAGMENTS, IMMUNOGLOBULIN 
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Descriptor English:   Immunoglobulin Fc Fragments 
Descriptor Spanish:   Fragmentos Fc de Inmunoglobulinas 
Descriptor Portuguese:   Fragmentos Fc das Imunoglobulinas 
Synonyms English:   Fc Fragment Immunoglobulins
Fc Fragment, Immunoglobulin
Fc Fragments
Fc Fragments, Ig
Fc Fragments, Immunoglobulin
Fc Immunoglobulins
Fragment Immunoglobulins, Fc
Fragments, Ig Fc
Ig Fc Fragments
Immunoglobulin Fc Fragment
Immunoglobulins, Fc
Immunoglobulins, Fc Fragment  
Tree Number:   D12.644.541.500.697
D12.776.124.486.485.538.500
D12.776.124.486.485.680.697
D12.776.124.790.651.538.500
D12.776.124.790.651.680.660
D12.776.377.715.548.538.500
D12.776.377.715.548.680.660
Definition English:   Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. 
Pharmacological Action:   Immunologic Factors
 
See Related English:   Receptors, Fc
 
History Note English:   2006 (1973) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PD pharmacology
PH physiology PO poisoning
RE radiation effects TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   22215 
Unique Identifier:   D007141 

Occurrence in VHL:
 

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